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1

Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice

Channappanavar, Rudragouda, Fehr, Anthony R., Vijay, Rahul, Mack, Matthias, Zhao, Jincun, Meyerholz, David K., Perlman, Stanley

Journal:

Cell Host & Microbe

Année:

2016

Langue:

english

Fichier:

PDF, 4.88 MB

english, 2016

2

ChemInform Abstract: Synthesis of 2-Bromo-1H-indenes via Copper-Catalyzed Intramolecular Cross-Coupling of gem-Dibromoolefins.

Peijun Liu, Kemei Tao, Liwen Zhao, Wang Shen, Jincun Zhang

Journal:

Année:

2012

Fichier:

PDF, 30 KB

2012

3

Synthesis of 2-bromo-1H-indenes via copper-catalyzed intramolecular cross-coupling of gem-dibromoolefins

Peijun Liu, Kemei Tao, Liwen Zhao, Wang Shen, Jincun Zhang

Journal:

Tetrahedron Letters

Année:

2012

Langue:

english

Fichier:

PDF, 831 KB

english, 2012

4

A study on antigenicity and receptor-binding ability of fragment 450–650 of the spike protein of SARS coronavirus

Jincun Zhao, Wei Wang, Zhihong Yuan, Rujing Jia, Zhendong Zhao, Xiaojun Xu, Ping Lv, Yan Zhang, Chengyu Jiang, Xiao-Ming Gao

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 933 KB

english, 2007

5

Immunization with an attenuated severe acute respiratory syndrome coronavirus deleted in E protein protects against lethal respiratory disease

Jason Netland, Marta L. DeDiego, Jincun Zhao, Craig Fett, Enrique Álvarez, José L. Nieto-Torres, Luis Enjuanes, Stanley Perlman

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2010

6

Development and evaluation of an enzyme-linked immunosorbent assay for detection of antibodies against the spike protein of SARS-coronavirus

Jincun Zhao, Wei Wang, Guang-Fa Wang, Yonghua Li, Hui Zhuang, Xiaoyuan Xu, Furong Ren, Zhendong Zhao, Xiao-Ming Gao

Journal:

Journal of Clinical Virology

Année:

2005

Langue:

english

Fichier:

PDF, 144 KB

english, 2005

7

Development of transgenic mice expressing a coronavirus-specific public CD4 T cell receptor

Zhao, Jingxian, Fett, Craig, Pewe, Lecia, Zhao, Jincun, Perlman, Stanley

Journal:

Journal of Immunological Methods

Année:

2013

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2013

8

Structural Basis for the Identification of the N-Terminal Domain of Coronavirus Nucleocapsid Protein as an Antiviral Target

Lin, Shing-Yen, Liu, Chia-Ling, Chang, Yu-Ming, Zhao, Jincun, Perlman, Stanley, Hou, Ming-Hon

Journal:

Journal of Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2014

9

Crystal structure-based exploration of the important role of Arg106 in the RNA-binding domain of human coronavirus OC43 nucleocapsid protein

Chen, I.-Jung, Yuann, Jeu-Ming P., Chang, Yu-Ming, Lin, Shing-Yen, Zhao, Jincun, Perlman, Stanley, Shen, Yo-Yu, Huang, Tai-Huang, Hou, Ming-Hon

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Année:

2013

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2013

10

Rapid generation of a mouse model for Middle East respiratory syndrome

Zhao, Jincun, Li, Kun, Wohlford-Lenane, Christine, Agnihothram, Sudhakar S., Fett, Craig, Zhao, Jingxian, Gale, Michael J., Baric, Ralph S., Enjuanes, Luis, Gallagher, Tom, McCray, Paul B., Perlman, S

Journal:

Proceedings of the National Academy of Sciences

Année:

2014

Langue:

english

Fichier:

PDF, 1.54 MB

english, 2014

11

T cell-mediated immune response to respiratory coronaviruses

Channappanavar, Rudragouda, Zhao, Jincun, Perlman, Stanley

Journal:

Immunologic Research

Année:

2014

Langue:

english

Fichier:

PDF, 661 KB

english, 2014

12

Passive Immunotherapy with Dromedary Immune Serum in an Experimental Animal Model for Middle East Respiratory Syndrome Coronavirus Infection

Zhao, Jincun, Perera, Ranawaka A. P. M., Kayali, Ghazi, Meyerholz, David, Perlman, Stanley, Peiris, Malik, Sandri-Goldin, R. M.

Journal:

Journal of Virology

Année:

2015

Langue:

english

Fichier:

PDF, 4.51 MB

english, 2015

13

Virus-Specific Regulatory T Cells Ameliorate Encephalitis by Repressing Effector T Cell Functions from Priming to Effector Stages

Zhao, Jingxian, Zhao, Jincun, Perlman, Stanley, Klein, Robyn

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 4.78 MB

english, 2014

14

Evasion by Stealth: Inefficient Immune Activation Underlies Poor T Cell Response and Severe Disease in SARS-CoV-Infected Mice

Zhao, Jincun, Zhao, Jingxian, Van Rooijen, Nico, Perlman, Stanley, Gale, Michael

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 2.32 MB

english, 2009

15

Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Regulates Cell Stress Response and Apoptosis

DeDiego, Marta L., Nieto-Torres, Jose L., Jiménez-Guardeño, Jose M., Regla-Nava, Jose A., Álvarez, Enrique, Oliveros, Juan Carlos, Zhao, Jincun, Fett, Craig, Perlman, Stanley, Enjuanes, Luis, Thiel, V

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 2.66 MB

english, 2011

16

Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus

Corti, Davide, Zhao, Jincun, Pedotti, Mattia, Simonelli, Luca, Agnihothram, Sudhakar, Fett, Craig, Fernandez-Rodriguez, Blanca, Foglierini, Mathilde, Agatic, Gloria, Vanzetta, Fabrizia, Gopal, Robin,

Journal:

Proceedings of the National Academy of Sciences

Année:

2015

Langue:

english

Fichier:

PDF, 1.69 MB

english, 2015

17

A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein

Li, Yan, Wan, Yuhua, Liu, Peipei, Zhao, Jincun, Lu, Guangwen, Qi, Jianxun, Wang, Qihui, Lu, Xuancheng, Wu, Ying, Liu, Wenjun, Zhang, Buchang, Yuen, Kwok-Yung, Perlman, Stanley, Gao, George F, Yan, Jin

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 4.24 MB

english, 2015

18

Middle East Respiratory Syndrome Coronavirus Causes Multiple Organ Damage and Lethal Disease in Mice Transgenic for Human Dipeptidyl Peptidase 4

Li, Kun, Wohlford-Lenane, Christine, Perlman, Stanley, Zhao, Jincun, Jewell, Alexander K., Reznikov, Leah R., Gibson-Corley, Katherine N., Meyerholz, David K., McCray, Paul B.

Journal:

The Journal of Infectious Diseases

Année:

2015

Langue:

english

Fichier:

PDF, 2.60 MB

english, 2015

19

MAVS expressed by hematopoietic cells is critical for control of West Nile virus infection and pathogenesis

Zhao, Jincun, Vijay, Rahul, Zhao, Jingxian, Gale, Michael, Diamond, Michael S., Perlman, Stanley

Journal:

Journal of Virology

Année:

2016

Langue:

english

Fichier:

PDF, 4.26 MB

english, 2016

20

Airway Memory CD4+ T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses

Zhao, Jincun, Zhao, Jingxian, Mangalam, Ashutosh K., Channappanavar, Rudragouda, Fett, Craig, Meyerholz, David K., Agnihothram, Sudhakar, Baric, Ralph S., David, Chella S., Perlman, Stanley

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 4.71 MB

english, 2016

21

Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus–Derived CD8 + T Cell Epitopes and Host MHC

Liu, William J., Lan, Jiaming, Liu, Kefang, Deng, Yao, Yao, Yanfeng, Wu, Shaolian, Chen, Hong, Bao, Lingling, Zhang, Haifeng, Zhao, Min, Wang, Qihui, Han, Lingxia, Chai, Yan, Qi, Jianxun, Zhao, Jincun

Journal:

The Journal of Immunology

Année:

2016

Langue:

english

Fichier:

PDF, 1.61 MB

english, 2016

22

The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection

Fehr, Anthony R., Channappanavar, Rudragouda, Jankevicius, Gytis, Fett, Craig, Zhao, Jincun, Athmer, Jeremiah, Meyerholz, David K., Ahel, Ivan, Perlman, Stanley

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 3.12 MB

english, 2016

23

DNA vaccine encoding Middle East respiratory syndrome coronavirus S1 protein induces protective immune responses in mice

Chi, Hang, Zheng, Xuexing, Wang, Xiwen, Wang, Chong, Wang, Hualei, Gai, Weiwei, Perlman, Stanley, Yang, Songtao, Zhao, Jincun, Xia, Xianzhu

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2017

24

Discovery of a novel canine respiratory coronavirus support genetic recombination among betacoronavirus1

Lu, Shuai, Wang, Yanqun, Chen, Yingzhu, Wu, Bingjie, Qin, Kun, Zhao, Jincun, Lou, Yongliang, Tan, Wenjie

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2017

25

MERS coronaviruses from camels in Africa exhibit region-dependent genetic diversity

Chu, Daniel K. W., Hui, Kenrie P. Y., Perera, Ranawaka A. P. M., Miguel, Eve, Niemeyer, Daniela, Zhao, Jincun, Channappanavar, Rudragouda, Dudas, Gytis, Oladipo, Jamiu O., Traoré, Amadou, Fassi-Fihri,

Journal:

Proceedings of the National Academy of Sciences

Année:

2018

Langue:

english

Fichier:

PDF, 956 KB

english, 2018

26

Differential Effects of IL-12 on Tregs and Non-Treg T Cells: Roles of IFN-γ, IL-2 and IL-2R

Zhao, Jingxian, Zhao, Jincun, Perlman, Stanley, Unutmaz, Derya

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.25 MB

english, 2012

27

A Rapid and Specific Assay for the Detection of MERS-CoV

Huang, Pei, Wang, Hualei, Cao, Zengguo, Jin, Hongli, Chi, Hang, Zhao, Jincun, Yu, Beibei, Yan, Feihu, Hu, Xingxing, Wu, Fangfang, Jiao, Cuicui, Hou, Pengfei, Xu, Shengnan, Zhao, Yongkun, Feng, Na, Wan

Journal:

Frontiers in Microbiology

Année:

2018

Langue:

english

Fichier:

PDF, 3.14 MB

english, 2018

28

Current understanding of middle east respiratory syndrome coronavirus infection in human and animal models

Wang, Yanqun, Sun, Jing, Zhu, Airu, Zhao, Jingxian, Zhao, Jincun

Journal:

Journal of Thoracic Disease

Année:

2018

Langue:

english

Fichier:

PDF, 1.69 MB

english, 2018

29

Single intranasal immunization with chimpanzee adenovirus-based vaccine induces sustained and protective immunity against MERS-CoV infection

Jia, Wenxu, Channappanavar, Rudragouda, Zhang, Chao, Li, Mingxi, Zhou, Haixia, Zhang, Shuyuan, Zhou, Panpan, Xu, Jiuyang, Shan, Sisi, Shi, Xuanling, Wang, Xinquan, Zhao, Jincun, Zhou, Dongming, Perlma

Journal:

Emerging Microbes & Infections

Année:

2019

Langue:

english

Fichier:

PDF, 3.66 MB

english, 2019

30

The pre-existing cellular immunity to Japanese encephalitis virus heterotypically protects mice from Zika virus infection

Zhang, Weihong, Xu, Yongfen, Zhao, Fanfan, Tarbe, Marion, Zhou, Shuru, Wang, Weihong, Zhang, Shengyuan, Zhang, Wei, Xu, Qiuping, Shi, Lina, Yuan, Feng, Lin, Xinwen, Liu, Shuai, Sun, Jing, Zhao, Jincun

Journal:

Science Bulletin

Année:

2019

Fichier:

PDF, 572 KB

2019

31

A novel luciferase immunosorbent assay performs better than a commercial enzyme-linked immunosorbent assay to detect MERS-CoV specific IgG in humans and animals

Wang, Wenling, Wang, Tianyu, Deng, Yao, Niu, Peihua, A, Ruhan, Zhao, Jincun, Peiris, Malik, Tang, Shixing, Tan, Wenjie

Journal:

Biosafety and Health

Année:

2019

Fichier:

PDF, 4.86 MB

2019

32

Complete Genome Sequences of Five Human Coronavirus NL63 Strains Causing Respiratory Illness in Hospitalized Children in China

Zhang, Lu, Gan, Mian, Zhang, Zhaoyong, Li, Xin, Liu, Wenkuan, Zhu, Airu, Sun, Jing, Li, Fang, Wang, Yanqun, Zhang, Fuchun, Zhao, Jingxian, Zhou, Rong, Zhao, Jincun, Roux, Simon

Journal:

Microbiology Resource Announcements

Année:

2020

Fichier:

PDF, 886 KB

2020

33

COVID-19 Severity Correlates with Weaker T Cell Immunity, Hypercytokinemia and Lung Epithelium Injury

Wang, Zhongfang, Yang, Xiaoyun, Zhou, Yumin, Sun, Jing, Liu, Xiaoqing, Zhang, Jing, Mei, Xinyue, Zhong, Jiaying, Zhao, Jincun, Ran, Pixin

Journal:

American Journal of Respiratory and Critical Care Medicine

Année:

2020

Fichier:

PDF, 456 KB

2020

34

Multiple approaches for massively parallel sequencing of SARS-CoV-2 genomes directly from clinical samples

Xiao, Minfeng, Liu, Xiaoqing, Ji, Jingkai, Li, Min, Li, Jiandong, Yang, Lin, Sun, Wanying, Ren, Peidi, Yang, Guifang, Zhao, Jincun, Liang, Tianzhu, Ren, Huahui, Chen, Tian, Zhong, Huanzi, Song, Wenche

Journal:

Genome Medicine

Année:

2020

Fichier:

PDF, 2.44 MB

2020

35

A Confirmed Case of SARS-CoV-2 Pneumonia with Routine RT-PCR Negative and Virus Variation in Guangzhou, China

Li, Zhengtu, Li, Yinhu, Chen, Lingdan, Li, Shaoqiang, Yu, Le, Zhu, Airu, Yang, Feng, Jiang, Qian, Chen, Liyan, Zhao, Jincun, Lu, Wenju, Zhong, Nanshan, Ye, Feng

Journal:

Clinical Infectious Diseases

Année:

2020

Fichier:

PDF, 1.44 MB

2020

36

Infectious SARS-CoV-2 in Feces of Patient with Severe COVID-19

Xiao, Fei, Sun, Jing, Xu, Yonghao, Li, Fang, Huang, Xiaofang, Li, Heying, Zhao, Jingxian, Huang, Jicheng, Zhao, Jincun

Journal:

Emerging Infectious Diseases

Année:

2020

Fichier:

PDF, 241 KB

2020

37

Elevated MUC1 and MUC5AC mucin protein levels in airway mucus of critical ill COVIDâ19 Patients

Lu, Wenju, Liu, Xiaoqing, Wang, Tao, Liu, Fei, Zhu, Airu, Lin, Yongping, Luo, Jieping, Ye, Feng, He, Jianxing, Zhao, Jincun, Li, Yiming, Zhong, Nanshan

Journal:

Journal of Medical Virology

Année:

2020

Fichier:

PDF, 249 KB

2020

38

Human postâinfection serological response to the spike and nucleocapsid proteins of SARSâCoVâ2

Xiao, Cheng, Ling, Shiman, Qiu, Minshan, Deng, Zhenxuan, Chen, Liping, Zhu, Airu, Chen, Yi, Liu, Yong, Lin, Xia, Lin, Fangmei, Wu, Qiubao, Shen, Lihan, Ye, Feng, Liu, Xiaoqing, Li, Yimin, Zhao, Jincun

Journal:

Influenza and Other Respiratory Viruses

Année:

2020

Fichier:

PDF, 667 KB

2020

39

The New Foe and Old Friends: Are We Ready for Microbiota-based Therapeutics in Treating COVID-19 Patients?

Peng, Ye, Zhao, Jincun, Tun, Hein M.

Journal:

Gastroenterology

Année:

2020

Fichier:

PDF, 281 KB

2020

40

Main protease of SARS-CoV-2 serves as a bifunctional molecule in restricting type I interferon antiviral signaling

Wu, Yaoxing, Ma, Ling, Zhuang, Zhen, Cai, Sihui, Zhao, Zhiyao, Zhou, Lingli, Zhang, Jing, Wang, Pei-Hui, Zhao, Jincun, Cui, Jun

Journal:

Signal Transduction and Targeted Therapy

Année:

2020

Fichier:

PDF, 1.34 MB

2020

41

Japanese Encephalitis Virus Vaccination Elicits Cross-Reactive HLA-Class I-Restricted CD8 T Cell Response Against Zika Virus Infection

Tarbe, Marion, Dong, Wei, Hu, Guang, Xu, Yongfen, Sun, Jing, Grayo, Solene, Chen, Xianyang, Qin, Chengfeng, Zhao, Jincun, Liu, Li, Li, Xiuzhen, Leng, Qibin

Journal:

Frontiers in Immunology

Année:

2020

Fichier:

PDF, 2.06 MB

2020